The Best Hotels in Italy:30. St. Regis Rome The St. Regis is in many ways fabulous, but its trump card is its unmatched attention to detail. From stylish touches like Murano glass lamps and painted frescoes, to the original artwork by Luca Pignatelli, Ubaldo Bartolini and Paolo Fiorentino, each of its 138 guest rooms and 23 suites feel unique and personal. The hotel’s Le Grand bar is considered by many as Rome’s best; order their signature Mediterranean Bloody Mary and decide for yourself.